Mýty o užívaní liekov na zníženie koncentrácie cholesterolu

Napísal Prof. MUDr. Michal Vrablík, Ph.D. 16. máj 2019

Užívanie liečiv na zníženie koncentrácie cholesterolu a ďalších tukov v krvi (predovšetkým tzv. statínov) patrí medzi základné opatrenia pri prevencii infarktu myokardu, cievnej mozgovej príhody a ďalších ochorení zapríčinených aterosklerózou.

tabletky lieky1200x800

V Slovenskej republike tieto lieky užíva viac ako milión pacientov, takže priamu alebo sprostredkovanú skúsenosť s nimi má takmer každý. V nasledujúcom texte sa pozrieme na niektoré „obľúbené“ omyly, ktoré sa udávajú v súvislosti s liekmi na znižovanie koncentrácie cholesterolu.

Koncentrácia cholesterolu po liekoch klesla, a preto ich môžem vysadiť

To celkom iste nie je pravda. Vysoká koncentrácia cholesterolu sa dá liečiť, ale nie celkom vyliečiť, pretože si pre ňu väčšinou nesieme genetickú (vrodenú) vlohu. Lieky fungujú len v prípade, že sú prítomné v organizme. Po prerušení liečby sa koncentrá- cie cholesterolu vracajú späť v priebehu niekoľkých dní. Preto treba lieky užívať trvalo.

Keď užívam statíny, nemusím dodržiavať zásady diéty

Ďalší obľúbený omyl. Diétne opatrenia pomáhajú nielen znižovať koncentráciu choles- terolu, ale upravujú aj ďalšie rizikové faktory aterosklerózy. Ich účinok sa vždy počíta a je prídavný k účinku liekov. Takže aj pre pacienta, ktorému lekár predpisuje tablety, má dodržiavanie diétnych a ďalších opatrení v oblasti životného štýlu zásadný význam.

Bojím sa vysokej dávky statínov

Obavy rozhodne nie sú na mieste. Dnes vieme, že vyššia dávka statínov chráni svoj- ho užívateľa účinnejšie ako dávka nižšia. Navyše väčšina (vzácnych) nežiaducich účinkov nemá priamu väzbu na dávku podávaného lieku a ich početnosť pri vyšších dávkach statínov nestúpa. Ak znášate dobre počiatočné dávky liekov, potom sa zvy- šovania dávky netreba obávať. Navyše, keď sa nežiaduci účinok po zvýšení dávky objaví, dá sa vrátiť k dávke pôvodnej alebo situáciu riešiť iným spôsobom.

Ak budem užívať statín dlhodobo, môže dôjsť k nepredvídaným nežiaducim účinkom

Skutočne chceme, aby statíny boli užívané dlhodobo; keď sa pre ne rozhodneme, ide o „doživotné“ rozhodnutie. Nie je však pravda, že by dlhší čas užívania prinášal riziká, súvisiace s dĺžkou liečby. Statíny používame viac ako 30 rokov a naďalej prebieha sledovanie ich bezpečnosti. Nemáme žiadne signály, že by dlhodobé užívanie statínov malo akékoľvek iné nežiaduce účinky ako tie, ktoré vzácne vznikajú pri krátkodobom užívaní.

Statíny sú nebezpečné

Zásadný omyl, bohužiaľ opakovaný v poslednom čase častejšie ako pravdy o priaz- nivých účinkoch týchto liekov. Statíny patria medzi vôbec najpreskúmanejšie liečivá a je pravdou, že ako všetky účinné liečivá majú aj nežiaduce účinky. Ich výskyt je však nízky a postihuje maximálne desatinu liečených. Väčšina z týchto nežiaducich účinkov je navyše plne vratných; v prípade, že sa objavia, vyriešime ich úpravou liečby. Hod- notenie bezpečnosti liečby patrí k bežnej praxi v rámci sledovania pacientov liečených statínmi, čo ďalej obmedzuje (veľmi nízke) riziko spojené s terapiou. Súhrnne statíny patria medzi najbezpečnejšie lieky a obavy nie sú na mieste.

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    It's true that they get a lot of work on chest day, but to maximize improvement, you should include a quantity of key movements.

    He’s a author and editor with a decade’s worth
    of experience covering health, health, tech and sports activities.
    In his spare time he enjoys health of all types, from deadlifts to lengthy runs, and is all the
    time on the lookout for his next problem. Hold a dumbbell in either hand and stand together with your legs broad, knees barely bent.
    Swing both dumbbells to 1 aspect and lift them
    up as if drawing a circle from hip degree to above shoulder height.

    In this section, I will spotlight the highest workout routines that focus on the three heads of the shoulders.

    Performing any of those would successfully goal the half in question. They not
    solely work the deltoids but also interact stabilizing muscle tissue, contributing to overall shoulder well being and strength.
    Machine workout routines are an excellent start line for beginners or
    these seeking managed and targeted deltoid coaching.
    Whether you’re chasing expertise just like the planche or just aiming for a balanced, strong-as-hell body, stable shoulders are a should.
    In calisthenics, it’s nearly unimaginable to focus on only one muscle
    group—especially with big ones just like the shoulders. Safety tipsMake positive your wrists,
    shoulders, and backbone are lined up properly.
    Extra reps imply extra training being carried out and extra
    stimulus for the muscles to grow. To compensate for shorter relaxation durations, you’d need to extend the
    variety of sets you do. Hypertrophy refers again to the enhance and growth of muscle cells, which makes
    you stronger and builds your endurance. It’s finest to follow a workout routine that comes with each compound and isolation workout routines for the best outcomes.

    The exercise will get its name from bodybuilder, actor, and politician Arnold Schwarzenegger who
    popularized the train. The Arnold press entails a dynamic range of motion, ranging from a bicep curl right into
    a rotating overhead press, which targets multiple parts of the
    shoulder muscular tissues. The rotation movement within the Arnold press engages the anterior,
    lateral, and posterior deltoids, providing
    an entire shoulder workout. Additionally, the overhead pressing motion further strengthens
    and develops the shoulder muscular tissues.
    Shoulder ache could be very debilitating, making even probably the most primary
    everyday activities like sleeping or brushing your teeth uncomfortable.
    Most lifters tend to emphasise the anterior head and pay too little consideration to the medial and rear heads.

    Needless to say, this oversight can harm your
    long-term progress. You’re on a mission to realize one easy
    aim – you need to build more muscle mass. You’re constant in the
    gym and hungry to get to that next degree. However
    the issue is you’re simply not making the positive aspects you anticipate.

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